2026-10-01T20:47:29Zhttps://phdtheses.ekt.gr/eadd_oai/requestoai:10442/14842024-07-06T15:41:55Zhdl_10442_2THE STUDY IS ABOUT THE PRECORNEAL TEARS FILM AND THE CONJUNCTIVAL EPITHELIUM. WE STUDY THE INFLUENCE OF THE AGE, SEX, ENVIRONMENTAL FACTORS AND GENERAL DISEASES (CONNECTIVE TISSUES DISEASES, S. SJOGREN) ON THE LACRIMAL FUNCTION AND THE CONJUNCTIVAL EPITHELIUM. WE EXAMINED FIVE GROUPS: 276 NORMAL PERSONS LIVING IN IOANNINA, 57 NORMAL PERSONS LIVING IN ATHENS, 50 PERSONS ONE WITH SUBJECTIVE SYMPTOMS OF DRY EYE, 33 WOMEN WITH CONNECTIVE TISSUES DISEASES WITHOUT SECONDARY S. SJOGREN AND 92 PERSONS WITH S SJOGREN. WE EXAMINATED THE LACRIMAL FUNCTION WITH BREAK-UP TIME, SCHIRMER-I TEST AND ROSE BENGAL STAINING AND THE CONJUCTIVAL EPITHELIUMS WITH IMPRESSION CYTOLOGY. THE ANALYSIS OF OUR RESULTS SHOW: THE LACRIMAL FUNCTION IS REDUCED BY THE AGE AND THIS CAUSE A SQUANOUS METAPLASIA OF THE CONJUNCTIVAL EPITHELIUM. SEX DOESN'T INFLUENCE TO THE LACRIMAL FUNCTION AND CONJUNCTIVAL EPITHELIUM. ENVIRONMENTAL FACTORS REDUCE THE STABILITY OF THE TEAR FILM. THE SUBJECTIVE SYMPTOMS MEAN THAT THE PROTECTION FROM THE TEAR FILM IT'S NOT ENOUGH FOR THE EYE. THE PATIENTS WITH S. SJOGREN SUFFER FROM DRY EYE WITH ASQUAMOUS METAPLASIA OF THE CONJUCTIVAL EPITHELIUM. THE ROSE BENGAL STAINING ISTHE MOST RELIABLE EXAMINATION FOR THE LACRIMAL FUNCTION. THE IMPRESSION CYTOLOGY IS A RELIABLE AND SIMPLE METHOD.ΔΡΑΣΕΙΣ ΤΩΝ ΓΛΥΚΟΚΟΡΤΙΚΟΕΙΔΩΝ ΣΤΟΥΣ ΝΕΥΡΩΝΕΣ ΤΟΥ Κ.Ν.Σ. ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΜΟΡΙΑΚΩΝ ΜΗΧΑΝΙΣΜΩΝ ΠΟΥ ΕΝΕΧΟΝΤΑΙ ΣΤΗΝ ΑΠΑΝΤΗΣΗ ΤΟΥ ΟΡΓΑΝΙΣΜΟΥ ΣΤΟ STRESSEFFECTS OF GLUCOCORTICOIDS ON CNS NEURONS: A CONTRIBUTION TO THE STUDY OF MOLECULAR MECHANISMS INVOLVED IN THE STRESS RESPONSEΜαρουλάκου, Ιωάννα1990greΕγκέφαλοςΕΛΑΖΥΜΙΚΗ ΔΡΑΣΤΙΚΟΤΗΤΑ ΤΗΣ GADΕΝΕΡΓΟΠΟΙΗΣΗ ΥΠΟΔΟΧΕΩΝ ΣΤΕΡΟΕΙΔΩΝΕπινεφριδεκτομέςΕΠΙΝΕΦΡΙΔΙΑΚΑ ΣΤΕΡΟΕΙΔΗΠΡΟΣΛΗΨΗ Γ'ΑΜΙΝΟΒΟΥΤΥΡΙΚΟΥ ΟΞΕΟΣ (GABA)ΠΡΩΤΕΟΛΥΣΙΣΣΥΝΑΠΤΟΣΩΜΑΤΑΥποδοχείς γλυκοκορτικοειδώνADRENAL STEROIDSAdrenalectomyBrainGABA UPTAKEGAD ACTIVITYGlucocorticoid receptorsProteolysisSTEROID RECEPTOR ACTIVATIONStressSYNAPTOSOMESNational and Kapodistrian University of AthensΕθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)Ιατρική και Επιστήμες ΥγείαςΕπιστήμες ΥγείαςMedical and Health SciencesHealth Sciences10.12681/eadd/1484http://hdl.handle.net/10442/hedi/1484PhD Thesis