Ποιοτικές μεταβολές της αρχιτεκτονικής του οστού στην περιοχή του αντιβραχίου και της κνήμης σε ασθενείς με ρευματοειδή αρθρίτιδα
Abstract
The purpose of this study was to investigate the influence of the rheumatoid arthritis on the bone architecture at the a) tibia and b) radius by peripheral Quantitative Computed Tomography (pQCT) Fifty-three postmenopausal women with RA and eighty-seven healthy control subjects, comparable in terms of age, body mass index and years since menopause, underwent peripheral Quantitative Computed Tomography (pQCT) at the non- dominant tibia. At 4% (trabecular site), a statistically significant decrease in trabecular BMC and vBMD (p < 0.001) was noted, while trabecular area was comparable. At 38% (cortical site), cortical BMC (p < 0.01), area (p < 0.05), and thickness (P < 0.001) were reduced in the RA group, whereas vBMD was comparable. Endosteal circumference was increased (p < 0.05), whereas periosteal circumference was comparable, indicating cancellization of cortical bone. At 14%, polar stress strength index was significantly decreased (p < 0.01) in RA patients, indicating impairmen ...
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